Wednesday, September 27, 2023
| TIME | DESCRIPTION | SPEAKER |
|---|---|---|
| Analytic Approaches to Utilize Outcome Measures in Clinical Trials | ||
| 9:00am-9:20am | Approaches to Defining Clinically Meaningful Change in Trial Outcome Measures | Jennifer Gewandter, PhD, MPH University of Rochester |
| 9:20am-9:40am | Creating MCID Thresholds in Veterinary Medicine: Estimating Minimal Clinically-Important Difference (MCID) for LOAD and COI | John F. Innes, BVSc, PhD, CertVR DSAS(orth),FRCVS University of Liverpool |
| 9:40am-9:50am | Discussion of Application of Success-Failure to Pain Outcome Measures: CBPI | Dottie Brown, MSCE, DVM, DACVS Mars Veterinary Health |
| 9:50am-10:10am | BREAK | |
| 10:10am-10:20am | Validated Scales for Assessing Acute Pain in Ruminants and Pigs: Approaches to Defining Success-Failure and What is Next? | Stelio Luna, DVM, Ms, PhD, DipECVAA, CVA (IVAS) São Paulo State University |
| 10:20am-10:30am | Success-Failure: Ground Reaction Forces | Michael Conzemius, DVM, PhD, DACVS Gilbert Queen Creek |
| 10:30am-10:50am | Use of AUC in Human Pain Studies | James N. Campbell, MD Centrexion Therapeutics |
| 10:50am-11:20am | Discussion: Analytic Approaches to Utilize Outcome Measures in Clinical Trials | Panel Discussion (Gewandter, Innes, Luna, Conzemius, Campbell) |
| 11:20am-12:30pm | LUNCH | |
| 12:30pm-12:50pm | Primary Endpoints: Single, Multiple Endpoints, or Composite Endpoints? | John T. Farrar, MD, PhD University of Pennsylvania |
| 12:50pm-1:10pm | Statistical Considerations When Using Multiple or Composite Endpoints | Claire Ruberman, PhD FDA CVM |
| 1:10pm-1:30pm | Examples of Use of Multiple or Composite Endpoints in Veterinary Species: Food Animals | Hans Coetzee, BVSc, Cert CHP, PhD, DACVCP, DACAW, DipECAWBM Kansas State University |
| 1:30pm-1:50pm | Adaptive and Other Innovative Pain Measurement Study Designs | Qiao Zhang, MS, PhD FDA CVM |
| 1:50pm-2:10pm | Discussion on Pros and Cons of Multiple / Composite Endpoints, Design Adaptations in Veterinary Clinical Pain Research | Panel Discussion (Farrar, Ruberman, Coetzee, Zhang) |
| 2:10pm-2:30pm | Open Discussion & Future Planning |
Registration is for an in person only meeting at NIH campus